malignancy

Noun

1. The state of being malignant or diseased.
2. A malignant cancer; specifically, any neoplasm that is invasive or otherwise not benign.
3. That which is malign; evil, depravity, malevolence.
   • [T]he malignancie of my fate, might perhaps diſtemper yours; […] - c. 1601–1602 (date written), William Shakespeare, “Twelfe Night, or What You Will”, in Mr. William Shakespeares Comedies, Histories, & Tragedies […]...
   • A cold wind swept down from it and set us shivering. Somewhere there, on that desolate plain, was lurking this fiendish man, hiding in a burrow like a wild beast, his heart full of malignancy against the whole race...
   • Because of the dearth of recent feminist writing about conditions in mental institutions, it's possible for us to image that they must have improved since the mid-'70s. Millett reminds us forcefully of the hellishness...