MPTP

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a byproduct of synthetic heroin, or MPPP, which causes parkinsonian symptoms in users; and a neurotoxin that degrades into MPP+ after crossing the blood-brain barrier, which causes a degradation of the dopaminergic neurons within the substantia nigra.

Noun

  1. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a byproduct of synthetic heroin, or MPPP, which causes parkinsonian symptoms in users; and a neurotoxin that degrades into MPP+ after crossing the blood-brain barrier, which causes a degradation of the dopaminergic neurons within the substantia nigra.
    • 2005 Dec 29, Petzinger, et al. Journal of Neuroscience Research http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16385585&query_hl=8&itool=pubmed_docsum The neurotoxicant...